Year in Review: The biggest hookups and breakups of 2012Related: 2012 Year In Review, Ashlee Simpson, Ashton Kutcher, Chris Brown, Demi Moore, Denise Richards
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Following months of rift rumors, Johnny Depp confirmed in June that his 14-year relationship with Vanessa Paradis was over. In a statement, he said they had "amicably separated" and asked for privacy for the sake of their two children, Lily-Rose and Jack.
The never-wed, low-key couple hadn't been seen together for a while before the split announcement, and the blame game soon began. He was henpecked, bored and in the midst of a midlife crisis; she was unhappy and bored with living in the French countryside.
Plus, there were those rumors of a blond third party …
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